Blar i NTNU Open på forfatter "Brown, Matthew A."
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Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trøndelag Health Study, Norway
Rostami, Sina; Hoff, Mari; Brown, Matthew A.; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)Objectives: To evaluate selection methods among published single-nucleotide polymorphisms (SNPs) associated with RA to construct predictive genetic risk scores (GRSs) in a population-based setting. Methods: The Nord-Trøndelag ... -
Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study
Williams, Camilla J.; Li, Zhixiu; Harvey, Nicholas; Lea, Rodney A.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Papadimitriou, Ioannis; Jacques, Macsue; Croci, Ilaria; Stensvold, Dorthe; Wisløff, Ulrik; Taylor, Jenna L.; Gajanand, Trishan; Cox, Emily R.; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Howden, Erin J.; Keating, Shelley E.; Yan, Xu; Bishop, David J.; Bye, Anja; Haupt, Larisa M.; Griffiths, Lyn R.; Ashton, Kevin J.; Brown, Matthew A.; Torquati, Luciana; Eynon, Nir; Coombes, Jeff S. (Peer reviewed; Journal article, 2021)Background Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is ... -
Prediction of Ankylosing Spondylitis in the HUNT Study by a Genetic Risk Score Combining 110 Single-nucleotide Polymorphisms of Genome-wide Significance
Rostami, Sina; Hoff, Mari; Brown, Matthew A.; Hveem, Kristian; Holmen, Oddgeir; Fritsche, Lars; Videm, Vibeke (Journal article; Peer reviewed, 2019)Objective The genetic component of ankylosing spondylitis (AS) development is ~90%. Of the known heritability, ~20% is explained by HLA-B27, and 113 identified AS-associated single-nucleotide polymorphisms (SNP) account ...